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Edward Roth was a graduate of Bellevue Hospital Medical College in New York city in 1880 after the required attendance of two years. The collection consists of ten volumes, the first five of which are Roth's notes on medical school lectures and clinics from 1878-1880. The remaining five include four volumes documenting his clinical practice in New Haven, 1891-1893, and one volume with a few entries on practice in Massachusetts in late 1893.